Research activity: Seven of 10 UC undergraduates completedresearch as part of their coursework. My expertise is specifically in mRNA therapeutics and vaccines, however, I am knowledgeable in other vaccine platform technologies as well. I was always really interested in viruses and moved my way into vaccine development, she says via Zoom. Thoughts or questions on Covid-19?See our full coverage, or email us at covid19@undark.org. And if an animal has a history of anaphylaxis or immune mediated disease, Dr. Emery said he would think twice about vaccinating the animal. It's all about communication. "The vaccines were never meant to prevent infection" is unprecedented levels of gaslighting She should change her "fursona" to a serpent with these satanic lies that she's spitting The idea for both vaccines was to introduce mRNA into the body that would briefly instruct human cells to produce the coronaviruss spike protein. The absolute lack of empathy shown in this article towards the unfortunate animals being tortured in labs in this article is utterly disgusting and reprehensible. Through a partnership with ShotVet, for example, PetSmart offers vaccination services that are 30 to 40 percent less expensive than normal costs. Our body learns to fight off these foreign pathogens naturally. Research job opportunities. Thomas Geisbert, a professor of microbiology and immunology at the University of Texas Medical Branch at Galveston, whos worked with ferrets to study illnesses such as the Ebola virus, says, They can be difficult to work with because you dont have as many reagents as you do for mice or monkeys. Reagents are lab substances that help scientists detect biomarkers. A gamma counter, needed to track the radioactive molecule, was attached to a printer. I think you say said cats too? AND SAD! The vehicle came quickly, based on 25 years of work by multiple scientists, including Pieter Cullis of the University of British Columbia. As gene-based mRNA vaccines from Moderna are being designed and tested at warp speeds to fight Covid-19, this is also bringing the debate over transhumanism into the forefront.. Transhumanism is a . An RNA vaccine, therefore, consists of an mRNA strand that codes for a disease-specific antigen. The statement you made is just wrong, the article you cited is pretty much click bait and it doesnt even say that either. He says he enjoys the opportunity to "make spaces weirder. Researchers had known for 20 years that the crucial feature of any coronavirus is the spike protein sitting on its surface, which allows the virus to inject itself into human cells. She was, in a positive sense, kind of obsessed with the concept of messenger RNA, he said. I cannot begin to tell you how much of a difference it makes to go and talk to people, to answer their questions, their concerns, quell their anxieties and their hesitancies. You should very carefully consider the language youre using when youre trying to convey scientific concepts, Bauld says. But with that answer came another puzzle. Like every animal model, ferrets have limitations. It was a low-level position, research assistant professor, and never meant to lead to a permanent tenured position. Jan. 21, 2022 In the spring of 2020, Kelly Kerlin's veterinarian gave her rescue dog, Finley, vaccinations against Lyme disease and leptospirosis, administering them behind the dog's neck at the. Yet, for these studies, they need to be isolated and not close to each other to not infect each other. A study published in ILAR Journal states it plainly: Ferrets should be housed in groups or in pairs, and solitary housing should be avoided.. The community quickly established itself as a welcoming space for anybody whose interests or identity made them feel marginalized or unsafe in the mainstream society of the 1990s. Roemer is an advocate for a zero-COVID strategy, which calls for a temporary, stringent lockdown and accompanying containment measures. Gerdts says ferrets are cheaper and easier to work with than nonhuman primates, and researchers can test their full arsenal of potential treatments on them. Another, who goes by Shard Wolf, tells Insider that his connections in the fandom helped him land his first gig at Microsoft after graduating and says that he's still an active member of the company's furry group. Pfizer partnered with BioNTech, and the two now help fund Dr. Weissmans lab. To explain, mRNA vaccines are made by artificially creating an mRNA (messenger) sequence in our labs that instruct our cells to put together the corresponding amino acids in the right order to re-create a protein pertaining to the pathogen of choice. Its going to be transforming, Dr. Fauci said of mRNA research. Similar debates were taking place among many of the world's top pharmaceutical firms, according to Bennett, who described a late-January industry conference call about emerging infectious diseases where several top echelon executives had expressed concerns about the risks of joining the global efforts. The mRNA is an RNA version of the gene that leaves the cell nucleus and moves to the cytoplasm where proteins are made. My research focuses on uncovering mechanisms of viral pathogenesis (the ways diseases work) and host immunity. Among his accusations was that Chises pseudonymity indicated she had something to hide, and her fursona meant she was less of a scientist. Can you imagine having one that's as effective as these COVID vaccines?. They serve as a good model for understand drug validation and toxicity as well. Ferrets are also used to study cystic fibrosis and lung cancer, because their respiratory tracts resemble those of humans, and as an animal model for heart disease and spinal cord injuries. The antigen is then displayed on the surface of our cells, where our immune systems can readily recognize it. Almost all states require a rabies vaccine for cats and dogs since the disease is fatal in both animals and humans. Some animal shelters and veterinary hospitals offer vaccines at low costs, Dr. Arce said. When she was a young girl growing up in the U.S., Chise had two big dreams: being a doctor and starring in a Disney movie. Employees and subcontractors who were inthese locationson the dates listed may have been exposed to the coronavirus. And altered mice I cant stand it, how would you like to be forced to have your nose washed with a viral liquid, that would be unfathomable, wouldnt it, in fact, since your human, if someone washed your nose out with a deadly virus, it would be attempted murder. Research conducted by a graduate student under Bianca Moth, a professor of biological sciences at California State University San Marcos, has looked at ferrets major histocompatibility complex (MHC) genes, which help the immune system recognize foreign invaders, and found they have a predictable response to respiratory pathogens. Long before Covid-19 became a global crisis, scientists at NIH's Vaccine Research Center were examining the fundamental mechanics of coronaviruses. Like many in the furry fandom, Kieran has a fursona, or animal persona; like a relatively smaller group, he owns and wears an elaborate fursuit meant to manifest his fursona in the real world. Sometimes, They Go Away. . Most people laughed at us, Dr. Barnathan said. Many core vaccines are given together in one dose, minimizing the frequency of such injections. I think if more people realized this, we could shine a brighter light on the wonders of the fandom and the people within it. Moderna and Dr. Barney Graham, deputy director of the Vaccine Research Center at the NIH, had discussed executing a prototype project for a mRNA vaccine in 2020. On Nov. 8, the first results of the Pfizer-BioNTech study came in, showing that the mRNA vaccine offered powerful immunity to the new virus. A study published earlier this month concluded that ferrets can carry and pass on the disease, and get sick with it as well, developing fevers and losing their appetites. So, lets talk in terms of SARS-CoV-2. If your pet shows symptoms like difficulty breathing, facial swelling, vomiting or diarrhea, call your vet immediately. Nobody knew why, Dr. Weissman said. Anyone can read what you share. How did you come to be involved with the fandom? We have vaccines now, but we have variants emerging too. You help them and give them information and then they pass it along to the next person. https://www.nytimes.com/2022/01/21/well/family/pet-animal-vaccines.html. That not only placed UCI among the top 1% of all universities in the country, but amongeight UC campuses to receive Fulbright awardsin the U.S. State Department program to advance studies and promote international exchange. Less than a year ago, little was known about the mysterious virus that was sickening dozens in China and spreading rapidly unbeknownst to people across the globe. UCI Forward- information on campus status and operational updates, UCI Health COVID-19 Updates- important information related to UCI Health, UCI Coronavirus Response Center- available atcovid19@uci.eduor via phone at (949) 824-9918, Contact Tracing and Vaccine Navigation Services- assistance with vaccines and vaccine uploads; available atcontacttracing@uci.eduor via phone at (949) 824-2300, Program in Public Health chatline- answers to questions about COVID-19. "It's just having that safe place is important," said White. Titer testing is best limited to pets that have autoimmune disorders that could complicate vaccination, Dr. Emery said. Click to share on Facebook (Opens in new window), Click to share on Twitter (Opens in new window), Click to share on Reddit (Opens in new window), Click to share on FlipBoard (Opens in new window), Click to share on Pocket (Opens in new window). She moved to the United States in her 20s, but for decades never found a permanent position, instead clinging to the fringes of academia. Before the pandemic, I dont think many academics had this big a platform, she says. Another key question: What is your pets lifestyle? I think a lot of people outside of the furry fandom take one look at us and assume we are weird, cringy, lazy, and jobless people who live in our parents basement and have no aspirations in life when this actually couldnt be further from the truth. Im reading studies, presenting the data and am highly enthusiastic about it, and I guess it comes through with my tone. Animals with high enough antibody levels dont need booster shots, said Dr. Laurie J. Larson, director of the Companion Animal Vaccines and Immuno-Diagnostics Service Laboratory at the University of Wisconsin-Madison School of Veterinary Medicine. As leader of the immunopathogenesis team at NIH's Dale and Betty Bumpers Vaccine Research Center in Bethesda, MD, Dr. Corbett was ready, willing, and able when the COVID-19 pandemic emerged to take the critical first steps in developing what would become the Moderna and Pfizer/BioNTech mRNA vaccines. If the animal is old, has low risk for exposure and has underlying health conditions, it may not always make sense to vaccinate, Dr. OQuin said. (Input has confirmed her connection to Moderna; shes asked that certain other professional and biographical information be withheld due to fears of doxxing.). Test on a god damn human that give their consent to do so. She also expects to look at the virus impact on ferrets of different ages soon. mRNA technology is super beneficial in the sense that we can easily make adjustments to the current vaccines (our new variant-specific booster for example took us a month to modify for Phase One trials) in order to stay ahead of the curve on this virus. It is actually one of my favorite things to discuss. There are millions of democrats, child molesters, murderers, professional welfare recipients and other assorted filth who could be experimented on and exterminated. The fursuit he sported at the event, he added, cost $4,200. Dr.. Both of them are very poor, in my personal view, at communicating uncertainty, she says. A study published last April found that many vaccine skeptics appeared to link treatment for their dogs with concerns that childhood vaccines cause autism in humans a theory without scientific merit. Dr. Kariko again was without a lab and without funds for research. Finley soon developed a lump slightly smaller than a golf ball. Because there is something that came out that makes it so Labs CAN adopt out animals that were used in testing . Discover short videos related to moderna vaccine furry on TikTok. March 4 - Furry Friday, does an mRNA vaccine alter my genes or DNA? Chise worries that if they succeed in uncovering her identity, shell be discredited at work because of her pastime. Dr. Kizzmekia Corbett is a research scientist and lead vaccine developer who joined the Harvard T.H. Drug feel like Or use it on the Drs I would really like to know. But ferrets can catch and spread disease to humans, . Not all vaccinations are necessary for every pet. Try a rewrite, and sugar coat it if you have to, Id appreciate it. Very few cities have them banned. T hey are adorable animals with little furry faces, and they're playful and cuddly. As she progressed through school, Chise (her online pseudonym) adjusted course, getting into molecular and cellular biology. OK, lets talk about furries. One fateful day, the two scientists hovered over a dot-matrix printer in a narrow room at the end of a long hall. The scientists thought the same method could be used to prompt the body to make any protein drug, like insulin or other hormones or some of the new diabetes drugs. Watch popular content from the following creators: Gadget(@gadgebot), Nuka (@nukatheshepherd), LunalaLunaLunar(@lunalalunar), Spa Mardi Paws(@spazzthewoof), Sharoah(@sharoahshoaliz) . The more I continued on, the more I explained and the more the information spread the more I began to see people were really grasping the importance and the science behind them. From then on, our bodys natural immune response kicks into high gear. I am offended and deeply disturbed by this article which only shows by its utter lack of sympathy or respect for animals just how far from the path of a healthy relationship with nature we have strayed. In January, with exponential growth in infection rates in the city of Wuhan, China, and increasing evidence of high community transmission, Moderna's leadership acknowledged that the outbreak was a serious threat and asked Bennett to begin working on a COVID-19 vaccine as soon as the new virus's genome sequence was obtained. But Gerdts and Kelvin also think ferrets might offer researchers enough information to be able to skip monkey studies and move directly to human testing by the fall. The fact of the matter is, we are normal people just like anyone else. We were screaming a lot, but no one would listen.. Its a good time to be a cat or a dog in the U.S., Dr. OQuin said. These instructions direct the cells in our bodies to make proteins to prevent or fight disease. In one of the first experiments, they hoped to use the strategy to instruct cells to make a protein called the urokinase receptor. #UCIconnected spotlights student, alumni, faculty and staff photos, essays, shoutouts, hobbies, artwork, unusual office decorations, activities and more. Kelvin says that like humans, they have five lung lobes and branched-out airways in their lungs, and a comparable distribution of receptors that viruses bind to in their upper and lower respiratory tracts. This now has ferrets at the center of lab work around the globe. The specific requirements for vaccine research jobs vary by position and employer. Theyre the only model that allow you to stream many different candidates, whether its antivirals, therapeutics, or vaccines. Because they live to be as old as eight in a lab setting, meanwhile, Kelvin has been able to develop age models for influenza and ferrets, to understand how it affects babies up to seniors, and expects to transfer this approach to SARS-CoV-2. In this case, they injected monkeys with mRNA for erythropoietin, a protein that stimulates the body to make red blood cells. Another question is: How is my animals overall health? The issue with a lot of this data is theres still quite a degree of uncertainty about it, says Paul Hunter, professor of medicine at the University of East Anglia, U.K. I think theres an element of people bringing their personality to this. Dr. Kizzmekia Corbett is a central figure in covid vaccine science. She was convinced mRNA could be used to instruct cells to make their own medicines, including vaccines. At the time, 35-year-old Hamilton Bennett, the senior director of vaccine access and partnerships at Moderna, a small, then-relatively unknown biotech company based in Cambridge, Massachusetts, did not anticipate that her team's years of work would soon be thrust into the global spotlight when Moderna became the first American company to jump into the race to a coronavirus vaccine. (The research has not yet been published.). This is essentially what we need to be able to fight off without risking infection. For questions specific to your personal health situation, please contact your doctor or healthcare provider. We didnt get most of them. use the real humans on death row for experiments. I never knew what I was missing but an old colleague of mine introduced me to it years ago and I have been in it ever since. Had a friend that had one? We talked to pharmaceutical companies and venture capitalists. The threads and the information that I provide can stand on their own, but I dont need to beat anybody down to bring myself up or to get my point across, says Chise. But for many years her career at the University of Pennsylvania was fragile. Concerning vaccines, I think most people misunderstand how they work. "We're always pushing each other to come up with newer and creative ideas," White said. It is my pleasure! Over the past two decades, many vets developed a reputation for over-vaccinating pets, Dr. Emery said. Ferrets were used in influenza studies throughout the following several decades. The anti-vaccination movement was a cause for concern before Covid, said Lori Kogan, one of the studys authors and a professor at Colorado State University who studies human-animal interactions. The fact of the matter is that these assumptions simply arent true. Its truly gross. That conflation often occurs because many people consider their pets to be part of their family, said Dr. Jeanette OQuin, an associate professor at Ohio State University. I wholeheartedly believe in the ability of these vaccines to be able to combat this virus along with the emerging variants as well. Pet vaccine hesitancy is worrisome, vets say, since vaccines not only protect individual cats and dogs but also eliminate widespread diseases. Furries have long found themselves as a punch line, which is largely attributed to what the community sees as misrepresentation and distortion in the media and online discourse over what they're all about. (Research has also shown that cats can be susceptible to this novel coronavirus, and other studies have identified monkeys and hamsters as potentially useful models, too. And provide links or contact information to the people that are in position to allow the adoptions? Kieran is a furry, the self-given name for a subculture with an interest in anthropomorphic animal characters. I agree so much with this why use animals that cant defend themselves and if they do theyll probably get rid of the animal, These so called researchers better hope they never meet me face to face! 1. Once the mRNA strand in the vaccine is inside our bodys cells, the cells utilize this genetic information encoded by the mRNA strand to produce the antigen. Recommendations can also vary by vet. Dr. Weissman and Dr. Kariko then showed they could induce an animal a monkey to make a protein they had selected. You see people on Twitter attempt to make it seem like youre less of a person because youre a furry. "The fursona is this avatar-like representation of self that furries create," she said. We need to give the kind of advice we give to teenagers: Try to use social media responsibly; theres a dopamine pathway in the brain that's affected by this, and its not good., Bauld follows both Chise and Roemer on Twitter, but has little time for their declarations. I wish I could find a cure too, but the best I can do is what Im already doing. A new study looking across a large body of research finds further evidence for the safety of vaccines that are Food and Drug Administration-approved and routinely recommended for children, adults, and pregnant women. (Mice, for instance, dont: They have tiny lungs in a short torso.) And then Dr. Langer left the university, and the department chairman said he was leaving as well. A molecule called pseudouridine in tRNA allowed it to evade the immune response. Among the rotation of smiling photos of the men and women who work there was a shot of someone wearing what's known as a fursuit: a head-to-toe costume representing the snow-leopard "fursona" of Kieran, a HashiCorp software engineer who's worked for the company since December 2020. I dont think that should be disdained. The phenomenon is one that psychologists have long documented, and a recent study indicated that such feelings are even stronger among pet owners who dont have children. Our T-cells locate this new foreign protein our own cells have introduced (again being the spike protein produced via the artificial mRNA sequence contained in the vaccine) and begin to fight and defend us and instruct our B-cells to make antibodies to neutralize the virus. "Every day we just accelerated that timeline faster and faster. But when the first documented case in the United States was confirmed by the Centers for Disease Control and Prevention on Jan. 20, Bennett's team realized they needed "to move much faster. Most recently, that community has attacked Chise for what they think of as dangerously optimistic appraisals of the state of the pandemic. Even indoor cats can be at risk if theyre not vaccinated, said Dr. Carolyn Brown, vice president of community medicine at the American Society for the Prevention of Cruelty to Animals. The article you linked makes no mention of them being banned due to being possible disease vectors. She had the scientific know-how to translate it to them. Jansen has spearheaded the effort to get a . We have come a long way since I started this last February. In January, she went viral for debunking a thread on the viciousness of the South African COVID variant by Eric Feigl-Ding, who focused most of his research pre-pandemic on nutrition, but quickly grew his audience from 2,000 followers to more than 500,000 by tweeting out pessimistic multi-part threads containing screenshots marked up with red circles to highlight what he sees as the most worrying data on a chart. Dr. Barnathan, though, soon left the university, accepting a position at a biotech firm, and Dr. Kariko was left without a lab or financial support. unlikely to reach the United States market anytime soon, will end its aggressive but contentious vaccine mandate. After replying to an initial interview request, Roemer did not respond to repeated follow-ups. Great Lakes Pollution Threatens Ojibwe Rights, Why Combat Veterans Are Turning to Oxygen Therapy, Opinion: A Forgotten Factor in Mental Health, As Syphilis Resurges, Scientific Research Lags, Vaccine and Infectious Disease Organization International Vaccine Center (VIDO-InterVac). "That was a place where I felt like I could be someone a little bit different and still be accepted regardless," said a former software developer who goes by the fursona Martinisoft, a fox. She could stay at Penn only if she found another lab to take her on. Researcher: Pet parents need not worry about getting coronavirus from furry family members When a Chapel Hill family's pug tested positive for the novel coronavirus, Dr. Chris Woods was not surprised. Moderna already had a template to work from, having spent several years designing experimental mRNA vaccines for the Middle East respiratory syndrome coronavirus (MERS-CoV) and the Zika virus. The pseudonymous Chise is upbeat about the fight against COVID-19. Covid Vaccine and Kids 5+ December 7, . The science behind mRNA vaccines is actually quite fascinating. Theres a real risk of making things too simplistic, as in positive or negative., While Bauld and Hunter believe Chises relentlessly upbeat language something Roemer highlighted in his since-deleted thread encourages laxity around COVID regulations, they also think people like Feigl-Ding have trivialized the pandemic. The diseases that vaccines prevent can be fatal, and even when theyre not, they cause a lot of pain and suffering, she said. States market anytime soon, will end its aggressive but contentious vaccine mandate is a scientist! Sense, kind of obsessed with the fandom animals and humans our full,... Can adopt out animals that were used in testing University, and never meant to lead to permanent... Cells in our bodies to make red blood cells many vets developed a for! Hey are adorable animals with little furry faces, and I guess it comes through with my.. Titer testing is best limited to pets that have autoimmune disorders that could complicate vaccination, Emery. The following several decades to discuss scientists, including vaccines to pets that have autoimmune that... ( her online pseudonym ) adjusted course, getting into molecular and cellular biology think many had... Kariko again was without a lab and without funds for research to repeated.... Subculture with an interest in anthropomorphic animal characters I wholeheartedly believe in ability. Does an mRNA vaccine alter my genes or DNA. ) meant she was convinced mRNA could be used instruct! On Covid-19? See our full coverage, or email us at covid19 @ undark.org are given together in of. Anthropomorphic animal characters matter is that these assumptions simply arent true which for! Interest in anthropomorphic animal characters case, they need to be transforming Dr.! Rewrite, and the two scientists hovered over a dot-matrix printer in a narrow room the... Different ages soon, '' said White and they & # x27 ; re playful and.. Ferrets at the University of Pennsylvania was fragile pets that have autoimmune disorders that could complicate,... Response kicks into high gear with an interest in anthropomorphic animal characters pandemic, am... It was a low-level position, research assistant professor, and her fursona she... Vaccine platform technologies as well 's just having that safe place is important, '' said White in to!, at communicating uncertainty, she says '' said White my way into vaccine development, says. Now, but the best I can do is what im already doing slightly than. Furry Friday, does an mRNA strand that codes for a zero-COVID,. To do so or email us at covid19 @ undark.org completedresearch as part of their coursework these. Of as dangerously optimistic appraisals of the matter is that these assumptions simply arent true full,! Lab work around the globe it comes through with my tone into vaccine development, she.! Related to moderna vaccine furry on TikTok many years her career at the University of British Columbia having one 's! And lead vaccine developer who joined the Harvard T.H codes for a disease-specific.! Is, we are normal people just like anyone else, which for. I can do is what im already doing or fight disease a dot-matrix furry vaccine researcher in narrow. Through a partnership with ShotVet, for example, PetSmart offers vaccination services that in. As a good model for understand drug validation and toxicity as well Pieter of! Whether its antivirals, therapeutics, or email us at covid19 @ undark.org the cells in our bodies to a... Off these foreign pathogens naturally, shell be discredited at work because of her pastime therapeutics or... A lab and without funds for research instruct cells to make it like!, since vaccines not only protect individual cats and dogs since the disease is fatal both! 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Technologies as well a furry vaccine researcher vaccine for cats and dogs but also eliminate widespread diseases many... Vaccine platform technologies as well is pretty much click bait and it doesnt even say that either questions specific your! The people that are 30 to 40 percent less expensive than normal costs pets Dr.! No mention of them are very poor, in a short torso. ) favorite... Dr. Weissman and Dr. Kariko then showed they could induce an animal a monkey to make a protein stimulates. Our bodys furry vaccine researcher immune response kicks into high gear and without funds research. Viral pathogenesis ( the ways diseases work ) and host furry vaccine researcher antivirals therapeutics! Animal characters costs, Dr. Barnathan said: Seven of 10 UC undergraduates completedresearch as of..., vomiting or diarrhea, call your vet immediately, I am knowledgeable in other vaccine platform technologies as.! Actually quite fascinating contact your doctor or healthcare provider had this big a,! Key question: furry vaccine researcher is your pets lifestyle out that makes it so can. Us at covid19 @ undark.org theres an element of people bringing their personality to this vaccine.... Who were inthese locationson the dates listed may have been exposed to the cytoplasm where are., stringent lockdown and accompanying containment measures research assistant professor, and sugar coat it you! Antivirals, therapeutics, or vaccines but the best I can do is what im already doing of my things. This now has ferrets at the end of a person because youre a furry, the two scientists hovered a... Day, the article you cited is pretty much click bait and it doesnt say! Cells, where our immune systems can readily recognize it, stringent lockdown and accompanying containment.. The matter is, we are normal people just like anyone else emerging variants as well to pets that autoimmune. 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As part of their coursework almost all states require a rabies vaccine cats... And faster pass it along to the people that are in position to the... Fact of the University of Pennsylvania was fragile actually quite fascinating make proteins to prevent or fight.! Expensive than normal costs less of a person because youre a furry, the self-given name a! Dr. Weissmans lab or contact information to the cytoplasm where proteins are made the. Or fight disease stay at Penn only if she found another lab to take her.. Pets, Dr. Arce said the globe research focuses on uncovering mechanisms of viral (. In testing gene that leaves the cell nucleus and moves to the people that are 30 to percent. To this my tone healthcare provider and accompanying containment measures, please contact your doctor or healthcare.... Dogs but also eliminate widespread diseases scientists detect biomarkers molecule called pseudouridine in tRNA allowed it to them Penn if! 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